Basic concepts of the drug eluting balloon industry
2024-06-11
The drug-coated Balloon (DCB) is a catheter-based Drug delivery device that combines balloon angioplasty with drug elution technology, so that drugs that inhibit cell proliferation are attached to the surface of the balloon. The drug-eluting balloon uses the balloon catheter as a delivery platform to deliver the drug inhibiting cell proliferation to the lesion site. During the expansion of the balloon, the drug can be released rapidly, in high concentration, evenly and in sufficient quantity at the lesion site and penetrate into the vascular wall, thus effectively inhibiting the hyperplasia of the vascular intima.
Source: CNKI, Tou Bao, Gao He Investment Research Center
The drug-eluting balloon has no metal mesh residue and no polymer matrix residue, which can reduce the inflammatory reaction. The non-long-term sustained-release technology can accelerate the healing and endothelialization of target lesions, thereby reducing the risk of late thrombosis and shortening the time of taking antiplatelet drugs. The original anatomical morphology and physiological contraction and diastole properties of the blood vessels were preserved, and the opportunity for follow-up treatment when necessary was preserved for the patients. Drug-eluting balloon can realize the idea of "intervention without implantation". After more than ten years of development, it has been widely used in the field of coronary artery and peripheral artery, and has shown high efficiency and safety. It has also begun to be gradually applied in the field of interventional therapy such as cerebrovascular and hemodialysis pathway stenosis. With the progress of medical device research and the accumulation of evidence-based medical evidence obtained by clinical research implementation, the unclear clinical difficulties are being further solved, while more clinical applications are also promoting the improvement of the production process, the future through the continuous update of technology and platform, drug eluting balloon can meet a wider range of clinical needs.
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